Plain-English translation of NCT06524505 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing deep transcranial magnetic stimulation (dTMS) as a treatment for bipolar depression. dTMS uses magnetic pulses delivered through a coil placed on your scalp to stimulate specific brain areas involved in mood regulation. The study will compare this active treatment to a sham (placebo) version to see if it reduces depression symptoms.
Many people with bipolar depression don't respond well enough to medications alone, or experience side effects that make treatment difficult. This trial is exploring whether this treatment could offer a safe, non-invasive option to help people feel better when added to their existing medications.
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If you join, you'll come in 5 days a week for 4 weeks (skipping weekends) for 20-minute treatment sessions where a magnetic coil is placed against your scalp. Half of participants will receive active stimulation and half will receive sham treatment (you won't know which). You'll have symptom assessments at weeks 2, 4, and 8, and blood samples taken at baseline, week 4, and week 8. Your existing psychiatric medications stay the same throughout the trial.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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