Plain-English translation of NCT06525545 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing the best way to recover after total ankle replacement surgery. Researchers want to know whether patients heal better and move more freely if they start moving their ankle right away after surgery, or if they should wear a cast for three weeks like the standard treatment. The study will compare how well each approach works by measuring pain, function, and how the ankle looks on X-rays.
Doctors want to find the fastest and safest way for patients to recover after ankle replacement surgery. Right now, the standard approach is to use a cast, but some evidence suggests that moving the ankle earlier might help patients return to normal activities sooner and with better long-term results.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will have ankle replacement surgery and then be randomly assigned to one of two recovery groups: either moving your ankle early with supervised exercises, or wearing a cast for three weeks. You'll visit the clinic regularly so doctors can check your healing progress, take X-rays, and ask you about your pain and how well your ankle is working. The study will track your recovery over several months to compare which approach gives better results.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
Italy
Sponsor
Istituto Ortopedico Rizzoli
Enrollment target
~72 participants
Started
October 2023
Primary completion
October 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in August 2024.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.