Plain-English translation of NCT06526195 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a heart pump device called HeartMate 3 can help people with advanced heart failure whose hearts are too weak to pump blood effectively on their own. Some patients will receive the device, while others will continue with their current medications. The trial is also studying how a special pressure-monitoring sensor can help doctors identify which patients are most likely to benefit from this device.
Many people with severe heart failure die or end up back in the hospital even when taking the strongest available medications. Doctors believe that identifying patients earlier—using pressure measurements from the heart—and offering them a mechanical heart pump might help them live longer and feel better.
You likely qualify if…
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If you qualify, you will first have a pressure-monitoring sensor placed in your heart blood vessels to measure pressures for at least 90 days while continuing your current medications. After that monitoring period, if your pressure readings are elevated, you may be randomly assigned to either receive the HeartMate 3 device (implanted surgically) or continue with medical therapy alone. You will have regular follow-up visits at the trial site to monitor how you're doing, and the trial will track your health, symptoms, and quality of life over time.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States