Finding the right dose when rheumatoid arthritis goes into remission

When rheumatoid arthritis improves and goes into remission, doctors don't yet have clear guidance on whether or how to reduce medication doses. This study tests adalimumab, a biologic medication that helps control inflammation. Researchers want to see if they can safely lower doses by checking the medication's level in your blood, rather than just watching for flares.

Right now, doctors have no established guidelines for safely reducing biologic medication when a patient's arthritis is doing well. Some evidence suggests flares are less likely when medication levels stay high enough, but no one knows exactly what that 'right level' should be for each person.