Plain-English translation of NCT06529029 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a newer form of electroconvulsive therapy (ECT)—a brain stimulation treatment that uses lower electrical current—to see if it reduces suicidal thoughts as effectively as standard ECT while potentially causing fewer memory problems. You would receive one of two types of treatment, and researchers would track how well each one helps with suicidal thoughts and your underlying mood or psychiatric condition.
Standard ECT is a proven, life-saving treatment for severe depression and other conditions that cause suicidal thoughts, especially when other treatments haven't worked. However, memory problems are a major concern that keeps many people from choosing this treatment. This study aims to find out whether the newer, lower-current version can be just as effective while being gentler on memory.
You likely qualify if…
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If you enroll, you would be randomly assigned to receive either the newer low-current brain stimulation treatment or standard ECT. Both treatments are given while you are asleep under anesthesia. You would attend ECT sessions according to your treatment plan (typically several sessions over weeks), and your doctors would monitor your suicidal thoughts, mood, and any cognitive side effects throughout the study. Your medications would generally remain the same unless there's an urgent need to change them.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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