Plain-English translation of NCT06529848 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether supervised exercise training can help people with a condition called coronary microvascular dysfunction — where the smallest blood vessels in the heart aren't delivering enough blood flow, even though the main arteries aren't blocked. About 100 people will either do 12 weeks of supervised exercise training (three sessions per week) or be in a control group. The study wants to see if exercise can improve how well these tiny blood vessels work and reduce chest pain symptoms.
Many people have chest pain and signs of reduced blood flow to the heart, but doctors find no blockages in the main coronary arteries. This condition, caused by dysfunction in the heart's smallest blood vessels, has no proven targeted treatment yet. Researchers believe exercise training might help restore proper blood vessel function and address the root causes of the problem.
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If you join this study, you'll be randomly assigned to either the exercise group or the control group. The exercise group will attend three supervised training sessions per week for 12 weeks, each lasting 40 to 50 minutes. The control group will continue their normal routine and be offered the same exercise training after the study ends. Throughout the study, you'll have heart imaging tests and other measurements to track how your condition changes.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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