Plain-English translation of NCT06536062 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing CB-PRP (cord blood enriched with platelet plasma) — a treatment made from umbilical cord blood — delivered as injections directly into the eye to help treat dry age-related macular degeneration (dry AMD). Dry AMD is a condition where the part of the eye responsible for central vision gradually breaks down, making it harder to see details. Researchers want to see whether this treatment is safe and whether it can help protect or restore vision in people with this condition.
Currently, there are no approved treatments that can stop or reverse vision loss from dry AMD. This medication is being tested because early research suggests that the healing and anti-inflammatory properties found in cord blood might help protect the cells in the retina that are damaged in this disease.
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Participants will be assigned to one of three injection schedules: monthly injections over 12 months, injections every two months over 12 months, or injections every three months over 12 months. In each schedule, one eye will receive the actual treatment while the other eye receives a sham (placebo) injection so researchers can compare results. Participants will have regular follow-up visits with advanced eye imaging to measure whether the treatment is helping protect their vision.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Italy
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Enrollment target
~36 participants
Started
July 2024
Primary completion
July 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
65 Years and older
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Maria Cristina Savastano, MD, PhD
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.