Plain-English translation of NCT06538402 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two different sizes for a surgically created pouch — either 10 centimeters or 15 centimeters — that replaces your colon in a procedure called ileal pouch-anal anastomosis (IPAA). Researchers want to understand which size gives patients the best bowel function and quality of life after surgery. You would be randomly assigned to receive one of the two pouch sizes during your scheduled surgery.
Doctors know that IPAA surgery helps patients with ulcerative colitis or familial adenomatous polyposis, but they're not certain whether a smaller or larger pouch leads to better outcomes in terms of how often you need to have bowel movements and how much this affects your daily life. This study will help surgeons decide which pouch size to use in the future.
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You would undergo your planned IPAA surgery at the hospital. During the operation, your surgeon would create either a 10 cm or 15 cm pouch and randomly assign you to one group. After surgery, you would be followed up as normal to monitor your bowel function, quality of life, and any complications. The study will track how often you have bowel movements and how the pouch size affects your daily activities.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Denmark
Sponsor
Odense University Hospital
Enrollment target
~120 participants
Started
July 2025
Primary completion
July 2028
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anders Mark-Christensen, MD, PhD
Odense University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.