A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy — Stella
Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
(216 sites) United States
Barnet Dulaney Perkins Eye Center-Ophthamalogy, Chandler, Arizona Barnet Dulaney Perkins Eye Center, Phoenix, Arizona Associated Retina Consultants, Phoenix, Arizona Retinal Research Institute, Phoenix, Arizona Retina Macula Institute of Arizona, Scottsdale, Arizona Retina Associates of Tuscan, Tucson, Arizona Retina Partners of Northwest Arkansas, PLLC, Springdale, Arkansas Retina Vitreous Associates Medical Group, Beverly Hills, California Retina Specialists of Beverly Hills- Department of Ophthalmology, Beverly Hills, California The Retina Partners, Encino, California Eye Medical Center of Fresno, Fresno, California Retina Consultants of Orange County, Fullerton, California Salehi Retina Institute dba Retina Associates of Southern California, Huntington Beach, California
Austria
Medical University Graz, Graz, Styria Medical University of Vienna, Vienna VIROS - Vienna Institute for Research in Ocular Surgery, Vienna Canada
Retina Centre of Ottawa - Department of Ophthalmology, Ottawa, Ontario Centre Hospitalier Universitaire de Quebec Universite Laval, Québec France
Centre Hospitalier Universitaire de Nice, Nice, Alpes Maritimes Hopital Saint Joseph, Marseille, Bouches Du Rhone Centre Hospitalier Universitaire De Poitiers, Poitiers, New Aquitaine Toulouse University Hospital, Toulouse, Occitanie Centre Hospitalier Intercommunal de Creteil, Créteil Centre Hospitalier Universitaire Francois Mitterrand, Dijon Hopital De La Croix-Rousse, Lyon Pole Vision Val d'Ouest, Lyon Centre Monticelli Paradis, Marseille Centre Hospitalier Universitaire de Nantes, Nantes Hopital Lariboisiere, Paris Germany
University of Ulm, Ulm, Baden-Wurttemberg Charite - Universitaetsmedizin Berlin, Berlin, Brandenburg Augenzentrum Frankfurt, Frankfurt am Main, Hesse Universitaetsklinikum Marburg, Klinik fuer Augenheilkunde, Marburg, Hesse Dietrich Bonhoeffer Klinikum, Neubrandenburg, Mecklenburg-Vorpommern Universitatsklinikum Bonn, Bonn, North Rhine-Westphalia Klinik fur Augenheilkunde Universitatsklinikum Dusseldorf, Düsseldorf, North Rhine-Westphalia Universitaetsklinikum Muenster, Münster, North Rhine-Westphalia Klinikum Ludwigshafen Augenklinik, Ludwigshafen am Rhein, Rhineland-Palatinate Saarland University Medical Center, Homburg, Saarland Knappschaftsklinikum Saar GmbH- Eye Clnic Sulzbach, Sulzbach, Saarland University Hospital Hamburg Eppendorf, Hamburg Hungary
Ganglion Medical Center, Pécs, Baranya University Of Szeged, Szeged, Csongrad-Csanad University Of Debrecen, Hungary, Debrecen, Hajdú-Bihar Semmelweis University, Budapest Budapest Retina Associates, Budapest Italy
University Hospital PTV, Rome, Lazio Fondazione Policlinico Gemelli, Rome, Lazio Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardy IRCCS MultiMedica, Milan, Lombardy Ospedale San Raffaele (HSR) - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Milano Azienda Ospedaliero Universitaria Careggi, Florence, Tuscany Azienda Ospedaliero Universitaria delle Marche, Ancona Universita degli Studi di Milano, Milan Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia, Rome Poland
Oftalmika Sp. z o.o., Bydgoszcz, Kuyavian-Pomeranian Voivodeship Caminomed, Tarnowskie Góry, Silesian Voivodeship Centrum Diagnostyki I Mikrochirurgii Oka Lens Sp zoo, Olsztyn, Warmian-Masurian Voivodeship Spain
Hospital Arruzafa, Córdoba, Andalusia Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona Hospital de Terrassa (Consorci Sanitari de Terrassa), Terrassa, Barcelona Oftalvist Clinic. IMED Hospital, Burjassot, Valencia Centro de Oftalmologia Barraquer, Barcelona Instituto de Microcirugia Ocular, Barcelona Institut Catala De Retina S.L., Barcelona Hospital Universitario Virgen Macarena, Seville Fundacion Aiken De La Comunitat Valenciana, Valencia Hospital Clinico Universitario Lozano Blesa. IIS Aragon, Zaragoza Miguel Servet University Hospital, Zaragoza United Kingdom
Liverpool University Hospitals NHS Foundation Trust-Royal Liverpool University Hospital, St Paul's Eye Unit-Ophthalmology, Liverpool, Merseyside York and Scarborough Teaching Hospitals NHS Foundation Trust, York, North Yorkshire University Hospitals Bristol NHS Foundation Trust, Bristol Moorfields Eye Hospital NHS Foundation Trust, Moorfields Eye Hospital, London Imperial College Healthcare NHS Trust, London The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne
Key details Sponsor
Regeneron Pharmaceuticals
Enrollment target
~975 participants
Primary completion
November 2027
Age range
50 Years – 85 Years
Last updated April 2026
Interested in joining? University of California Irvine, Irvine, California
University of California San Diego, Jacobs Retina Center, La Jolla, California South Coast Retina Center, Long Beach, California American Institute of Research, Los Angeles, California Kaiser Permanente Los Angeles Medical Center, Los Angeles, California Jules Stein Eye Institute in David Geffen School of Medicine at Ucla, Los Angeles, California Retinal Consultants Medical Group Inc Modesto, Modesto, California Northern California Retina Vitreous Associates Medical Group, Inc., Mountain View, California California Retina Consultants, Oxnard, California Desert Retina Consultants, Palm Desert, California California Eye Specialists Medical Group Inc., Pasadena, California Retina Consultants San Diego, Poway, California California Eye Specialists Medical Group, Inc., Redlands, California Optic Eye Care, Rowland Heights, California UC Davis Health Eye Center, Sacramento, California Vrmg Inc, Sacramento, California Retinal Consultants Medical Group (RCMG) - Greenback Lane Retina Center, Sacramento, California West Coast Retina Medical Group, Inc., San Francisco, California Orange County Retina Medical Group, Santa Ana, California Macula Retina Vitreous Research Institute, Torrance, California University of Colorado, Aurora, Colorado Retina Consultants of Southern Colorado, Colorado Springs, Colorado Retina Specialists of Colorado - Denver, Denver, Colorado Southwest Retina Research Center, Durango, Colorado Colorado Retina - Lakewood, Lakewood, Colorado Eye care Center of Northern Colorado doing business as Advanced Vision Research Institute, Longmont, Colorado Retina Group of New England, Waterford, Connecticut Advanced Retina Institute-Ophthalmology, Bonita Springs, Florida Advanced Research, Coral Springs, Florida Retina Group of Florida, Fort Lauderdale, Florida National Ophthalmic Research Institute, Fort Myers, Florida ClearVista Clinical Research, Retina Center Tampa Bay, Hudson, Florida Florida Retina Institute, Jacksonville Perimeter Park- Ophthalmology, Jacksonville, Florida Florida Retina Consultants, Lakeland, Florida Bascom Palmer Eye Institute, Naples, Florida Florida Retina Institute - Orlando, Orlando, Florida Retina Care Specialists, Palm Beach Gardens, Florida Eye Associates of Pinellas, Pinellas Park, Florida Retina Group of Florida, RAS-Sarasota Retina Center-Ophthalmology, Sarasota, Florida Retina Vitreous Associates of Florida Saint Petersburg, St. Petersburg, Florida University of South Florida Ophthalmology, Tampa, Florida Center for Retina and Macular Disease, Winter Haven, Florida Southeast Retina Center, Augusta, Georgia Georgia Retina - Marietta, Marietta, Georgia University of Illinois at Chicago, Chicago, Illinois Retinal Vitreal Consultants, Chicago, Illinois The University of Chicago, Chicago, Illinois University Retina and Macula Associates PC - Lemont, Lemont, Illinois Illinois Retina Associates, Oak Park, Illinois Springfield Clinic Main Campus East, Springfield, Illinois Retina Associates, LLC, Lenexa, Kansas University of Louisville, Louisville, Kentucky Retina Associates New Orleans, Metairie, Louisiana Ross Davis Retina, Metairie, Louisiana Ochsner Health, New Orleans, Louisiana Eye Assoc. of NE LA dba Haik Humble Eye Ctr, West Monroe, Louisiana Eye Associates of Northeast Louisiana dba Haik Humble Eye Center, West Monroe, Louisiana The Retina Care Center, Baltimore, Maryland The Retina Group of Washington, Chevy Chase, Maryland Cumberland Valley Retina Consultants-Ophthalmology, Hagerstown, Maryland Mid Atlantic Retina Specialist, Hagerstown, Maryland Massachusetts Eye And Ear Infirmary, Boston, Massachusetts Opthalmic Consultants of Boston, Boston, Massachusetts New England Retina Consultants, PC, Springfield, Massachusetts Retina Associates of Michigan, Grand Blanc, Michigan Mississippi Retina Associates, Madison, Mississippi Deep Blue Retina Clinical Research PLLC, Southaven, Mississippi Retina Research Institute, LLC, St Louis, Missouri Mid Atlantic Retina - Cherry Hill, Cherry Hill, New Jersey New Jersey Retina, Teaneck, New Jersey New Jersey Retina, Toms River, New Jersey Vision Research Center at Eye Associates of New Mexico, Albuquerque, New Mexico University of New Mexico, HSC, Albuquerque, New Mexico Sight MD, Brentwood, New York Retina Vitreous Surgeons of Central New York, PC, Liverpool, New York MaculaCare, PLLC, New York, New York New York Ear & Eye- East 85th, New York, New York Northwell Health- Manhattan, Ear, Eye and Throat Hospital- Ophthalmology, New York, New York Retina Associates of New York, Upper East Side, New York, New York Seeta Eye center, Poughkeepsie, New York Western Carolina Retinal Associates, Asheville, North Carolina NC Retina Associates, Cary, North Carolina Graystone Eye, Hickory, North Carolina North Carolina Retina Associates, Wake Forest, North Carolina Piedmont Retina Specialist, Winston-Salem, North Carolina Cincinnati Eye Institute, Cincinnati, Ohio University Hospitals Cleveland Medical Center, Cleveland, Ohio The Ohio State University, Columbus, Ohio Midwest Retina, Inc, Dublin, Ohio Retina Vitreous Center - Edmond, Edmond, Oklahoma Tulsa Retina Consultants, Tulsa, Oklahoma Verum Research LLC, Eugene, Oregon Retina Northwest, The Highlands Building, Portland, Oregon EyeHealth Northwest, Portland, Oregon OHSU-Casey Eye Institute, Marquam Hill-Ophthalmology, Portland, Oregon Cascade Medical Research Institute LLC, Springfield, Oregon Mid Atlantic Retina, Bethlehem, Pennsylvania Erie Retinal Surgery & Erie Retina Research, Erie, Pennsylvania Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, Pennsylvania Vision Research Solutions - the Eye Institute, Philadelphia, Pennsylvania Sewickley Eye Group, Sewickley, Pennsylvania Retina Consultants of Carolina, Greenville, South Carolina Charleston Neuroscience Institute LLC, Ladson, South Carolina Charleston Neuroscience Institute, LLC, Mt. Pleasant, South Carolina Palmetto Retina Center, West Columbia, South Carolina Black Hills Regional Eye Institute, Rapid City, South Dakota Tennessee Retina, PC, Nashville, Tennessee Vanderbilt Eye Institute, Nashville, Tennessee Retina Research Institute of Texas, Abilene, Texas Austin Research Center for Retina, Austin, Texas Austin Retina Associates, Austin, Texas Austin Clinical Research LLC, Austin, Texas Retina Consultants Texas, Bellaire, Texas Star Retina PLLC, Burleson, Texas Retina Foundation of the Southwest, Dallas, Texas Texas Retina Associates, Dallas, Texas University of Texas Southwestern Medical Center, Dallas, Texas Retina Consultants of Texas, Katy, Texas Valley Retina Institute, P.A., McAllen, Texas Red River Research Partners (Formerly AXIS Clinical), Plano, Texas Austin Retina Associates, Round Rock, Texas Medical Center Ophthalmology Associates, San Antonio, Texas Retina Associates of South Texas, San Antonio, Texas Retina Consultants of Texas, San Antonio, Texas Retina Consultants of Texas Brown Retina Institute, San Antonio, Texas Retina Center of Texas, Southlake, Texas Retina Consultants Texas, The Woodlands, Texas Tyler Retina Research Institute- Ophthalmology, Tyler, Texas Retina Associates Of Utah Retina Specialist, Salt Lake City, Utah Rocky Mountain Retina Consultants, Salt Lake City, Utah Salt Lake Retina- Ophthalmology, West Jordan, Utah University of Vermont, Burlington, Vermont Southeastern Retina Associates, Bristol, Virginia Retina Group of Washington, Fairfax, Virginia Piedmont Eye Center, Lynchburg, Virginia Virginia Eye Institute, Richmond, Virginia Retina Institute of Virginia, Richmond, Virginia Spokane Eye Clinical Research, Spokane, Washington West Virginia University Eye Institute, Morgantown, West Virginia University Medical Center of the Johannes Gutenberg-University Mainz, Mainz
St. Franziskus-Hospital, Münster