Plain-English translation of NCT06542224 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a surgical implant called deep brain stimulation (DBS) for people with severe obsessive-compulsive disorder (OCD) who haven't improved with standard treatments like medications or cognitive behavioral therapy. Researchers will place tiny electrodes in your brain and use advanced computer analysis to understand which brain signals predict how well the treatment works. The goal is to create personalized treatment plans that work better for each individual patient.
About 20% of people with OCD don't respond to standard medications or therapy, leaving them with severe symptoms that greatly disrupt their daily life. This trial aims to identify brain-based markers that could help doctors personalize this treatment and predict which patients will benefit most from the procedure.
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You would undergo surgery to have electrodes implanted in your brain, connected to a small stimulator device placed under your skin (similar to a pacemaker). After implantation, the research team will continuously record your brain signals and monitor your symptoms over time using both clinical assessments and advanced computer analysis. This allows doctors to understand how your brain activity relates to your OCD symptoms and to fine-tune your personalized treatment settings.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
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