Plain-English translation of NCT06543563 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether , added to a standard sedation medication called dexmedetomidine, can improve brain monitoring during deep brain stimulation surgery for Parkinson's disease. During this surgery, doctors place electrodes in the brain to help control Parkinson's symptoms, and they need to monitor your brain's electrical signals in real time. The study wants to see if the new combination medication keeps you comfortable while allowing surgeons to get clearer signals from your brain.
Parkinson's patients undergoing this brain surgery need to be sedated and comfortable, but many sedation medications can interfere with the brain signals surgeons rely on to place the electrodes correctly. This medication may offer comfort without disrupting those critical brain signals, and early research suggests it might also help with sleep problems, depression, and anxiety that often accompany Parkinson's.
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If you join this study, you will undergo your scheduled deep brain stimulation surgery at Beijing Tiantan Hospital. During surgery, you will receive either the standard sedation medication alone or the standard medication combined with , depending on which group you are randomly assigned to. Surgeons will monitor your brain's electrical signals throughout the procedure, and you will be followed after surgery to check for any complications and to see how the medication affected your sleep, mood, and other symptoms.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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