Plain-English translation of NCT06548191 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This research is testing whether time-restricted eating—a pattern where you eat only during certain hours of the day and fast for longer periods at night—might help people with mild cognitive impairment or Alzheimer's disease. The idea is that aligning your meals with your body's natural daily rhythms may support brain health and slow down cognitive decline. Researchers will check whether this eating pattern is safe and practical for older adults, and measure changes in markers related to aging and brain disease.
Alzheimer's disease and memory problems are devastating conditions with limited treatment options. Recent research suggests that our body's internal clock plays an important role in how we process nutrients and may affect brain health, so this trial explores whether timing our meals differently could help slow disease progression.
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Depending on which group you join, you will either start the time-restricted eating pattern right away for 6 months, or continue your normal eating schedule for the first 3 months and then switch to the new eating pattern for the next 3 months. Throughout the study, you'll visit the research center for cognitive tests and blood work, wear a device to track your sleep and activity, and keep a simple daily log of when you eat. The study lasts either 3 or 6 months depending on your group assignment.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
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