Plain-English translation of NCT06548867 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why some patients with advanced kidney cancer respond well to —a medication that slows cancer growth—while others don't benefit from it. This study will collect and analyze tumor tissue samples from two groups of patients: those whose cancer stayed under control for at least 9 months and those whose cancer progressed within 3 months. By comparing the genetic profiles of these groups, the team hopes to identify genetic markers that predict who will benefit most from this treatment.
Currently, doctors cannot reliably predict which patients will respond well to this medication before starting treatment. By identifying genetic differences between patients who respond well and those who don't, researchers hope to eventually personalize treatment decisions and help more patients avoid ineffective therapies.
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You won't need to visit a clinic or undergo any new procedures. Researchers will use tumor tissue that was already collected from your surgery or biopsy (within the last 5 years) and already stored in a hospital. Your medical records will be reviewed to understand how you responded to the treatment. The study will analyze the genetic makeup of your tumor tissue and compare it with other patients' samples to identify patterns that explain treatment response.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
Italy
Sponsor
Gruppo Oncologico Italiano di Ricerca Clinica
Collaborators
Yghea, Ipsen
Enrollment target
~80 participants
Started
May 2024
Primary completion
June 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Carmine Pinto, MD
AUSL/IRCCS of Reggio Emilia
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.