Plain-English translation of NCT06551662 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether drug-coated balloons—special balloons that deliver medication to prevent artery re-narrowing—work as well as or better than traditional drug-eluting stents for a specific type of heart artery blockage called a bifurcation lesion (where the artery branches into two). You would be randomly assigned to receive one of three treatments: a paclitaxel drug-coated balloon, a sirolimus drug-coated balloon, or a standard drug-eluting stent.
Branching coronary artery blockages are challenging to treat, and doctors want to know if the newer drug-coated balloon approach might be simpler and equally effective compared to stents, which sometimes require a second procedure if they re-narrow over time.
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You will undergo a coronary angioplasty procedure in which doctors will prepare your blockage and then randomly assign you to one of three treatment groups. After the procedure, you will return for scheduled follow-up visits to check how well the treatment is working and to monitor for any complications. The study involves standard heart catheterization and imaging, with visits timed according to the protocol.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
Italy
Poland