Sound waves and gel versus ultrasound therapy for knee arthritis pain

This study compares two different physical therapy approaches for knee osteoarthritis—a common condition where the cartilage in the knee gradually wears down. One group will receive ultrasound therapy combined with a special chitosan nanoparticle gel and a guided exercise program, while another group will receive a different treatment. Researchers will use artificial intelligence technology to measure changes in the knee joint structure and function over time.

Many current treatments focus on the cartilage itself, but recent research suggests that changes in the bone beneath the cartilage may be just as important—or even more important—in causing knee arthritis pain and damage. This trial is exploring whether targeting both the bone and soft tissues with the new treatment approach can help reduce pain and slow down joint damage.