Brain stimulation to reduce involuntary movements from Parkinson's medication

This study is testing a noninvasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help people with Parkinson's disease who develop involuntary movements — called dyskinesia — from long-term use of levodopa medication. The treatment targets a specific area of the brain involved in movement control. Researchers want to find out whether delivering the stimulation in short bursts at different frequencies can reduce these troubling involuntary movements and improve quality of life.

Many people with Parkinson's disease develop involuntary movements as a side effect of their long-term levodopa treatment, which can significantly interfere with daily activities. This trial exists because earlier research suggested that targeted brain stimulation might help control these movements, and now researchers want to test which stimulation pattern works best.