Plain-English translation of NCT06570954 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a therapy called Retraining and Control Therapy (ReACT) for adults who experience non-epileptic seizures—seizures that look real but don't come from epilepsy in the brain. The therapy is delivered online and focuses on two key areas: helping you feel more in control of your symptoms and changing unhelpful thoughts about what seizures mean. Researchers believe that by addressing these thought patterns, they can help reduce how often seizures happen.
Many people with non-epileptic seizures struggle with feeling helpless and develop catastrophic expectations about their symptoms, which can actually make seizures worse. This trial exists because there's a need for treatments specifically designed to rebuild your sense of control and challenge the fearful thoughts that may be fueling your seizures.
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You'll come to the University of Alabama at Birmingham for a baseline visit lasting about 2.5 hours, where you'll complete questionnaires, computer tasks, and provide saliva samples to measure stress response. You'll then be randomly assigned to start therapy right away or wait 3 or 6 months. During the waiting period (if assigned), you'll track your seizures weekly from home. Once therapy begins, you'll receive 12 sessions of Retraining and Control Therapy delivered over videoconference. You'll also wear a special watch for one week to track your sleep and seizures, and return for follow-up visits to measure your progress.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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