Plain-English translation of NCT06571149 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether intravenous thrombolysis—an injectable medication that dissolves blood clots in the brain—can help people recover better from an acute ischemic stroke (a stroke caused by a blood clot) when they are already taking direct oral anticoagulants (a type of prescription blood thinner). The study will compare people who receive this medication plus standard stroke care to people who receive standard stroke care alone, and will track their recovery over 90 days.
Many stroke patients are already on blood thinners to prevent clots from other conditions, but doctors have been uncertain whether giving this medication is safe and effective in that situation. This trial aims to provide clear answers about whether this treatment helps these patients recover better.
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If you join this study, you will be randomly assigned to receive either the clot-busting medication plus standard stroke care, or standard stroke care alone. You will receive your assigned treatment in the hospital during the acute stroke phase. The research team will follow your recovery and check how you are doing at 90 days after your stroke to see which group had better outcomes.
AI-generated summary from trial data · Oct 7, 2026 · Not medical advice
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