Testing a New Antibody Treatment for Heart Artery Disease

This trial is testing whether a medication called meplazumab can help people with coronary artery disease (narrowing of the heart's arteries). The study is based on the idea that inflammation plays a big role in how plaque builds up in arteries, and this medication is designed to target that inflammation. Researchers want to see if the medication is safe and whether it actually works to reduce fatty deposits in the arteries.

Coronary artery disease is a serious condition where plaque narrows the arteries that supply blood to your heart. Even when patients take standard medications, some people remain at high risk for heart attacks. Scientists believe that reducing inflammation in the artery walls could help prevent this plaque from getting worse, and this medication is a new way to try that approach.