Plain-English translation of NCT06576830 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing , a long-acting pain medication, given one time during tonsil surgery to see if it helps children and teens manage pain better after surgery. Researchers will compare this medication to the standard short-acting pain medications doctors normally use. The goal is to find out if the medication reduces how much additional pain relief children need after they wake up from surgery.
After tonsil surgery, children often have significant pain that can be hard to manage with standard medications. This study is looking for better ways to control pain after this common surgery so children recover more comfortably and may need fewer doses of other pain medications.
You likely qualify if…
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If you join, you will receive either the new medication or the standard pain medication during your tonsil surgery—you won't know which one. After surgery, the research team will track how much pain you have and whether you need additional pain relief. You'll answer daily surveys for 7 days after surgery, then the team will call you for check-ins at 30 days, 3 months, and 6 months to see how your recovery is going.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Phase
Post-approval monitoring
Sponsor
Duke University
Collaborators
National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Enrollment target
~440 participants
Started
November 2024
Primary completion
December 2028
Age range
3 Years – 17 Years
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lisa M Einhorn, MD
Duke University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.