Plain-English translation of NCT06580392 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This study is testing Cardiac Contractility Modulation (CCM), a device implanted in your heart that sends gentle electrical signals to help your heart pump better. The researchers want to see if this device makes it easier for your doctors to adjust your heart failure medications to the best doses for you, and whether it helps more patients reach their treatment goals.
Many people with heart failure struggle to get their medications adjusted to the right doses, which can limit how well they feel and function. This trial is testing whether the device can help doctors optimize medications more effectively and help more patients achieve the full benefits of guideline-recommended heart failure treatment.
You likely qualify if…
You likely don't qualify if…
If you qualify for the main study arm, you would receive the Optimizer device implant and then return for follow-up visits at about 3 months, 6 months, and 12 months. At these visits, your doctors will check how you're doing, adjust your medications if needed, and measure how well the device is working. If you don't quite qualify for the main arm, you may still participate in a registry where you'd continue your regular care and complete similar follow-up assessments.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Italy
Sponsor
Impulse Dynamics
Enrollment target
~200 participants
Started
February 2025
Primary completion
June 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2025.
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Central contact
Gary Cranke
Impulse Dynamics
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.