Plain-English translation of NCT06580639 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why some people who are exposed to tuberculosis develop the disease while others don't. This study uses a special blood test called a mycobacterium growth inhibition assay (MGIA) to measure how strong each person's immune system is at fighting tuberculosis. By comparing this immune response in healthy people, people recently exposed to TB, and people with TB infection, the researchers hope to better predict who is at risk and improve how TB is diagnosed and monitored.
Right now, doctors don't have a good way to measure how well a person's own immune system is controlling tuberculosis. This test could help identify who is truly at risk of developing active TB and who is successfully fighting off the infection on their own, which could lead to better treatment decisions.
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If you join this study, you will visit a clinic at an infectious disease department where a healthcare worker will draw 40 milliliters of blood from your arm—similar to a standard blood test. Your blood sample will then be used to perform the growth inhibition assay, which measures how well your immune cells fight tuberculosis in the laboratory. The entire process takes less than an hour, and there is no ongoing treatment or multiple visits required.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Sweden
Sponsor
Linkoeping University
Enrollment target
~280 participants
Started
August 2020
Primary completion
March 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Thomas Schoen, Professor
Linkoeping University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.