Plain-English translation of NCT06581302 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called Magnetic Seizure Therapy (MST) combined with antipsychotic medication for people with psychosis. MST is a newer, gentler version of a procedure called electroconvulsive therapy that has been used for decades to treat severe psychiatric conditions. The study will compare how well the combination of MST plus medication works compared to medication alone.
Many people with psychosis don't respond well enough to antipsychotic medications alone, and doctors need better treatment options. While the older brain stimulation procedure (electroconvulsive therapy) can help, it sometimes causes memory and thinking problems. This trial is testing whether the newer magnetic version offers similar benefits with fewer side effects on memory and thinking.
You likely qualify if…
You likely don't qualify if…
If you are randomly chosen to receive the new treatment, you would come in five times a week for 2 weeks to receive the magnetic brain stimulation sessions under anesthesia, plus your regular antipsychotic medication. If you are in the comparison group, you would take antipsychotic medication alone. Either way, after the first 2 weeks, all participants continue with standard psychiatric care while the research team tracks your progress for another 4 weeks.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China
Sponsor
Shanghai Jiao Tong University School of Medicine
Enrollment target
~50 participants
Started
September 2024
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 55 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jijun Wang, M.D, Ph.D
Shanghai Mental Health Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.