Plain-English translation of NCT06584448 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how the brain uses a substance called acetate, and whether this process differs in people who drink heavily versus those who don't. This study will use advanced brain imaging called Deuterium Metabolic Imaging (DMI) combined with MRI scans to measure acetate use in different brain regions. The study also looks at stress hormones and drinking patterns to see if there are connections.
Scientists believe that understanding how the brain processes acetate in people with alcohol use disorder could help explain why some people drink heavily and lead to better treatments in the future.
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Participants will first complete a phone screening and an in-person intake visit with interviews, questionnaires, and blood work. If eligible, you'll return for a brain imaging study day where you'll receive an intravenous infusion of a labeled acetate solution over two hours while undergoing brain scans. You'll also complete some cognitive tests. The entire study involves a few visits over several weeks, and researchers will compare your brain imaging results with your stress hormone levels and drinking patterns.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States