Plain-English translation of NCT06585254 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called transcutaneous vagus nerve stimulation (tVNS) — a non-invasive device you wear that gently stimulates a nerve in your neck — to see if it can reduce the exhaustion, widespread pain, brain fog, and post-exertion crashes that plague people with long COVID. Researchers will compare two ways of using the device to find out which approach works better for your symptoms.
Long COVID affects hundreds of thousands of people, but there are currently no proven treatments to relieve the debilitating fatigue and pain. An earlier small study showed promise with this nerve stimulation approach, so researchers want to test it more thoroughly to help people like you get relief.
The entire study happens from home — no clinic visits required, and you can continue your current treatments. You'll use a small nerve stimulation device daily for 35 minutes over 6 weeks. You'll either adjust the device yourself to a comfortable level each day, or the device will automatically find your personalized settings. The research team will monitor your progress remotely throughout the study.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
United States
Enrollment target
~50 participants
Started
November 2024
Primary completion
December 2026
Age range
21 Years – 70 Years
Last updated on clinicaltrials.gov in August 2026.