Plain-English translation of NCT06585254 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing transcutaneous vagus nerve stimulation (tVNS)—a noninvasive treatment where a small device gently stimulates a nerve in your neck—to see if it can improve symptoms of long COVID, particularly fatigue, widespread pain, brain fog, and post-exertional malaise. Researchers will compare two ways of using the device over 6 weeks to find out which approach works best for patients.
Many people continue to suffer from long COVID months after infection, but there are currently no proven treatments. This trial aims to test whether the treatment can safely help reduce the disabling symptoms that keep people from living their normal lives.
You will use a small vagus nerve stimulation device at home for 35 minutes each day for 6 weeks. Depending on which group you're assigned to, you will either control the device settings yourself by ramping up the stimulation until it feels slightly uncomfortable and then adjusting it back, or the device will automatically adjust its settings based on built-in software. The entire study is done remotely—you will not need to visit a medical center, and you can continue any treatments you are currently receiving.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States