Plain-English translation of NCT06587165 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are studying how the heart can naturally grow and repair itself in young children with heart disease. This trial uses a special marker called N15-thymidine to measure how many new heart muscle cells are being made in babies and infants who are already scheduled for heart surgery. The goal is to understand whether we can one day harness the body's own repair abilities to treat heart failure.
Unlike skin or other organs that can repair themselves throughout life, the heart loses most of its ability to grow new muscle cells after birth. Doctors don't fully understand when and how quickly this happens, or how it changes in children with heart disease. If researchers can measure this process, it may lead to new ways to help sick hearts heal themselves.
You likely qualify if…
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If your child qualifies, they will receive a harmless marker (N15-thymidine) for a set period before their already-scheduled heart surgery. During the surgery, doctors will collect a small sample of heart tissue that would normally be removed as part of the surgical procedure. This tissue sample will then be analyzed to measure how many new heart muscle cells are present. No additional surgery or visits are needed beyond the care your child is already receiving.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States