Plain-English translation of NCT06587828 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying immune cells called T cells that attack the body in autoimmune diseases like Crohn's disease, ulcerative colitis, celiac disease, multiple sclerosis, and others. By collecting tissue samples during procedures you're already having (like colonoscopies) and matching blood samples, the study team will identify which T cells are actively causing inflammation. This information will help them develop new, more targeted treatments in the future.
Current autoimmune treatments work for some patients but not others, and they can have side effects. By understanding exactly which T cells are attacking which tissues in each disease, doctors hope to create personalized treatments that work better and have fewer complications.
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If you qualify, you'll donate tissue samples during a planned medical procedure (such as a colonoscopy for inflammatory bowel disease patients or a small intestine biopsy for celiac disease patients) along with matching blood samples. For some patients, researchers may collect samples from both inflamed and normal areas of tissue. The tissue and blood will be studied using specialized technology to identify disease-causing immune cells. There is no long-term follow-up; participation is primarily the tissue and blood collection during or around your clinical procedure.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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