Plain-English translation of NCT06595654 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing repetitive transcranial magnetic stimulation (rTMS) — a non-invasive procedure that uses magnetic pulses to stimulate specific areas of the brain — to help reduce negative symptoms of schizophrenia. Negative symptoms are those that involve a loss or reduction of normal abilities, such as difficulty expressing emotions or motivation. The study will test four different treatment schedules to see which works best and is most tolerable for patients.
People with schizophrenia often struggle with negative symptoms even when taking antipsychotic medications, and there are limited treatment options. This trial is exploring whether brain stimulation might provide additional relief for these persistent symptoms, and establishing safe, effective protocols for using this treatment in real-world clinical settings.
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Depending on which treatment schedule you are assigned to, you will receive brain stimulation sessions lasting 20–50 minutes. Some schedules involve one session per day for 4 weeks, while others involve multiple sessions per day for 2 weeks. Each session uses magnetic pulses delivered through a coil placed against your scalp. After your treatment ends, you will be followed for 3 months to monitor how you respond and whether any symptoms return.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
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