Plain-English translation of NCT06596746 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
MARKERS-NDD is a long-term study that follows people diagnosed with brain diseases—including Parkinson's, Alzheimer's, and related conditions—as they receive their regular medical care. Researchers will collect information from your visits, including how you walk and move, brain imaging, memory tests, and blood work. They'll use artificial intelligence to analyze all this data together, looking for patterns that could help doctors diagnose these diseases earlier and predict how the disease might progress.
Right now, brain diseases like Parkinson's and Alzheimer's are diagnosed fairly late, after significant damage has already occurred. There are no treatments that can stop these diseases from progressing. This study exists to find early warning signs in movement, brain scans, and blood tests—so doctors can identify the disease sooner and eventually develop better treatments.
You likely qualify if…
You likely don't qualify if…
You will continue your normal medical visits at the research center, and during those visits, researchers will collect additional information. This includes recording how you walk and move (using motion sensors or video), having brain imaging scans, completing memory and thinking tests, answering questions about your symptoms, and providing blood samples. The study is designed to fit into your regular clinical care, so you won't need extra appointments beyond what you'd normally have—researchers simply gather data from the visits you're already making.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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