Plain-English translation of NCT06597851 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is trying to understand the connection between two conditions: tiny blood vessel problems in the heart and insulin resistance (difficulty processing sugar). Researchers want to see if people whose hearts struggle to process blood sugar efficiently are more likely to have problems with the smallest blood vessels that feed their heart muscle. The study involves heart imaging, blood tests, and a special test that measures how your body handles insulin.
Many patients experience chest pain and signs of heart strain, but when doctors look at their major coronary arteries, they appear normal. This study exists to understand if small blood vessel problems—combined with difficulty processing sugar—might explain why these patients still suffer from heart symptoms.
You will visit the hospital for heart imaging tests including an ultrasound of your heart and a coronary angiography (where a thin tube is passed through your blood vessels to see inside your arteries). You'll also have blood tests to measure how your body handles sugar. On a separate visit, you'll undergo a hyperinsulinemic-euglycemic clamp test—a specialized procedure that measures how your body responds to insulin. After these initial tests, you'll have brief follow-up visits or phone calls at 6 and 12 months to check on your health.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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