Plain-English translation of NCT06599658 on ClinicalTrials.gov ↗ · Source last updated ·
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing the best way to give COVID-19 booster shots and flu vaccines to people whose immune systems are weakened by conditions like transplants, HIV, or autoimmune diseases. The study will compare giving these vaccines at different times and intervals to see which approach helps people's bodies respond best and stay protected. Researchers want to find the safest and most effective vaccination schedule for this vulnerable group.
People with weakened immune systems are at much higher risk of serious illness and death from COVID-19 and the flu compared to healthy people. While booster shots can help strengthen protection in these patients, doctors aren't sure about the best timing for giving multiple vaccines together, so this study will help answer that important question.
You likely qualify if…
You likely don't qualify if…
You will be assigned to one of four groups that differ in how often you receive COVID-19 boosters (every 3 or 6 months) and when you receive your flu vaccine (at the start or 1 month later). Over the course of the study, you'll visit the clinic for vaccinations and have blood tests taken to measure how well your immune system is responding. The study will track your health and vaccine responses over time to determine which schedule works best for people like you.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Canada