Plain-English translation of NCT06600321 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This study is testing a new medication called to see if it can help treat advanced liver cancer that has spread or cannot be removed with surgery. Researchers want to understand how safe this medication is and how well it works — both when given by itself and when combined with an existing cancer immunotherapy drug called . The goal is to find the right dose and learn whether this treatment could become a new option for people with this type of cancer.
Current treatments for advanced liver cancer don't work well enough for everyone, and many patients need better options. This trial is exploring whether this medication, which targets a specific genetic pathway found in some liver cancers, might offer a new way to help patients fight their disease.
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You will receive the study medication as injections or infusions on a regular schedule, either alone or combined with infusions. The study has two phases: first, researchers will test different doses in small groups to find the safest and most effective dose, and then they will enroll more patients to confirm how well the medication works. You will need to visit the clinic regularly for blood tests, imaging scans, and check-ins to monitor how you're responding and watch for any side effects.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
United States