Plain-English translation of NCT06606535 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is investigating whether aromatase inhibitors—a common hormone therapy used to treat breast cancer—affect how well patients think, remember, and concentrate. Researchers will compare cognitive function in breast cancer patients taking this medication with healthy women of similar ages, using brain imaging and thinking tests to see if there are differences.
Some breast cancer patients report feeling 'foggy' or having trouble concentrating during hormone therapy, but doctors don't fully understand why this happens or how common it really is. This study aims to clarify whether the medication causes these cognitive changes and to explore connections with other symptoms of low estrogen, like hot flashes.
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If you join this study, you'll visit the clinic during a regular follow-up appointment. You'll answer detailed questions about your medical history and any symptoms you're experiencing, then complete thinking and memory tests with trained staff on the same day. Additional brain imaging and eye scans will be scheduled separately based on what works for you and the clinic. The study is observational, meaning you won't be asked to change your current treatment—researchers are simply watching and measuring how the therapy affects your cognition over time.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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