Plain-English translation of NCT06608134 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This early-stage trial is testing whether injections of Wharton's Jelly—a natural tissue from umbilical cords—can safely treat knee osteoarthritis (arthritis caused by wear and tear). Researchers will give different doses of this tissue to 120 participants and watch them for one year to see if it reduces pain and improves how well their knees work.
Knee arthritis affects millions of people and current treatments don't always provide long-term relief. This medication uses natural tissue that may help reduce inflammation and support healing in damaged joints, offering a new option for people who struggle with chronic knee pain.
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You will receive a single injection of the umbilical cord tissue directly into your knee joint. You'll be randomly assigned to receive one of three different doses. Over the next 12 months, you'll visit the clinic multiple times for check-ups, pain assessments, imaging scans, and blood tests to track whether the injection is safe and whether your pain and knee function improve.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States