Plain-English translation of NCT06615102 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
After heart surgery, some patients develop sudden kidney injury, which can be serious and affect recovery. This trial is testing whether , a medication that helps regulate blood pressure and kidney function, might prevent this complication better than the standard treatment (noradrenaline). Both medications are given through an IV to maintain healthy blood pressure during and after surgery.
Up to 30% of heart surgery patients develop acute kidney injury, which increases hospital stays, complications, and costs. Current blood pressure medications sometimes don't work well enough in certain situations after surgery, so researchers want to see if this medication—which works through a different biological pathway—might better protect the kidneys.
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If you join this trial, you will be randomly assigned to receive either or the standard blood pressure medication (noradrenaline) through an IV line during and after your heart surgery. Both groups aim to keep blood pressure at safe levels. The research team will monitor your kidney function, blood pressure, and other vital signs closely during your hospital stay and will follow up with you afterwards to track your recovery and any effects on your kidneys.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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