Plain-English translation of NCT06615492 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During lung transplant surgery, doctors sometimes use a machine called ECMO (extracorporeal membrane oxygenation) to temporarily take over the work of your heart and lungs while the surgical team replaces your diseased lungs with healthy donor lungs. This trial is testing whether using ECMO from the start of every surgery is better than waiting to use it only if your heart and lungs struggle during the operation. The goal is to figure out which approach leads to fewer complications after surgery and better recovery.
Lung transplant surgery is complex and can be hard on the heart and lungs during the operation. Doctors want to know if routine use of this heart-lung support machine prevents dangerous drops in blood pressure and oxygen levels, or whether selective use—only when problems develop—works just as well while potentially avoiding unnecessary risks.
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If you join this trial, you will be randomly assigned to one of two groups before your lung transplant surgery. One group will receive routine ECMO support from the beginning of the operation; the other group will have ECMO available but only used if your surgical team determines you need it during the procedure. Either way, you will undergo lung transplant surgery as planned, and your medical team will closely monitor your heart and lungs throughout and after the operation. The trial does not add extra clinic visits beyond standard lung transplant care.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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