Plain-English translation of NCT06616194 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Migraine research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing , a tablet that dissolves in your mouth, to see if it can help prevent migraine attacks in teenagers who have migraines 8 or more days each month. Half of the participants will take every other day for 3 months, and the other half will take a placebo (a tablet with no medicine in it) that looks identical. If the medication works, all participants who continue can then take it for a full year to make sure it stays safe with long-term use.
Teens with chronic migraines need better ways to prevent attacks before they start, not just treat them after they begin. This trial will help doctors understand whether this medication can reduce how often migraines happen and improve quality of life for young people dealing with frequent, debilitating headaches.
You would visit the clinic about every 4 weeks for up to 19 visits over 15 months, with some visits possibly done at home. At each visit, you'll have a health check and blood sample taken. You'll take either the study medication or placebo every other day for the first 3 months, then everyone who continues takes the medication for a full year. Throughout the study, you'll fill out a simple daily diary to track your migraine attacks so doctors can see how well the treatment works.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
United States