Plain-English translation of NCT06619405 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Age-Related Macular Degeneration research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how the light-sensitive cells in your eye (called rods) work in people with age-related macular degeneration (AMD) — a condition that affects central vision as people age. This study will measure how quickly your eyes adjust when you move from bright light to darkness, and then see if that ability is connected to how well you can read and move around safely. By studying people with different stages of AMD and people with healthy eyes, the researchers hope to find new ways to help predict and possibly treat vision problems.
As AMD progresses, many people struggle with everyday activities like reading and getting around in dim lighting. Doctors don't yet fully understand why some people have more trouble than others, or how changes in the eye's ability to adjust to darkness connect to real-world vision problems. This study aims to fill that gap and may help doctors better predict who will have the most difficulty with daily tasks.
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You will visit Duke University or University of Alabama at Birmingham for testing. During your visit, you'll have a comprehensive eye exam, take a reading test, and complete measurements of how quickly your eyes adjust when moving from light to darkness. You'll also do a mobility test to see how well you can move around. The researchers will collect information about your age, background, medical history, and current medications. The study is designed to be diagnostic, meaning it's focused on measurement and testing rather than treating a condition.
AI-generated summary from trial data · Aug 26, 2026 · Not medical advice
United States