Plain-English translation of NCT06620458 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This research study is looking at a heart treatment called paclitaxel drug-coated balloon angioplasty, which is used to open clogged arteries in the heart. Researchers want to understand what factors help predict whether this treatment will work well for each patient, and they'll follow participants for up to 10 years to see how durable the results are. Some participants will also donate blood samples to help scientists find biological markers that could improve how doctors choose and perform this treatment in the future.
While this medication has been used to treat blocked heart arteries, doctors don't fully understand which patients benefit most or what specific techniques lead to the best long-term results. This large study aims to identify the factors that make the treatment more or less successful, so future patients can receive more personalized and effective care.
If you join this study, you will receive the standard drug-coated balloon treatment for your heart artery blockage. Additionally, researchers will collect information about your health history, take blood samples at the start, and perform follow-up visits at scheduled times—particularly at 1 year and continuing for up to 10 years—to check your progress and assess how well the treatment continues to work. Some participants will also have special imaging tests of their heart vessels during or after the procedure to help doctors understand what's happening inside the artery.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
China
Sponsor
Henan Institute of Cardiovascular Epidemiology
Enrollment target
~5,000 participants
Started
October 2024
Primary completion
December 2025
Age range
18 Years and older
Last updated on clinicaltrials.gov in October 2026.