Plain-English translation of NCT06620523 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether a combination of CoQ10 and Glutathione—two natural compounds your body uses for energy and protection—can prevent acute kidney injury in people having heart surgery with cardiopulmonary bypass. About 30% of patients develop kidney problems after this type of surgery, which can be serious. The medication aims to protect kidney cells from damage during the surgery.
When your heart is stopped during surgery and then restarted, your kidneys can be temporarily starved of oxygen, which damages cells. This trial exists because there are currently no proven ways to prevent this damage, and researchers believe protecting the energy centers of kidney cells might help.
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You will take capsules by mouth before and after your heart surgery—either the active supplements or a placebo (inactive look-alike pill), decided by chance. You'll be monitored during your hospital stay and follow-up visits to see how well your kidneys recover. The study involves 242 participants total and aims to determine whether this treatment can reduce kidney complications from heart surgery.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United States
Phase
Testing effectiveness
Sponsor
George Washington University
Enrollment target
~242 participants
Started
July 2024
Primary completion
June 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in October 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Eduard Shaykhinurov, MS
George Washington University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.