Plain-English translation of NCT06620562 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether , a combination weight-loss medication, can help people who have had sleeve gastrectomy surgery (a procedure that makes the stomach smaller) lose even more weight and improve their health. Half the participants will take this medication for two years after surgery, while the other half will take a placebo (a pill with no active ingredient). Both groups will also receive support for healthy eating and behavior change.
Sleeve gastrectomy surgery helps people lose weight, but not everyone loses as much weight as they need to feel better and resolve weight-related health problems. Researchers want to know if adding this medication after surgery can help people achieve better long-term results.
You likely qualify if…
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You would have sleeve gastrectomy surgery first. About one month after surgery, you would start taking either the active medication or a placebo pill twice a day, gradually increasing the dose over several weeks based on how your body tolerates it. You would continue taking this medication (or placebo) for 24 months while attending regular visits to check your weight, health, and how you're doing. Throughout the trial, you'll receive support from the research team about nutrition and healthy eating habits.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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