Plain-English translation of NCT06623669 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a program called MORPH-III that combines two proven strategies: increasing daily physical activity through movement and improving diet to achieve modest weight loss. The study involves older adults (65+) with chronic knee or hip arthritis pain and aims to see whether this combined approach can reduce pain, help people move more comfortably, and improve overall quality of life.
Many older adults with chronic arthritis pain have few good non-medication options for managing their condition. Earlier small studies suggested this combination program might help, but researchers need to test it with more people over a longer time to confirm it really works and see if the benefits last.
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If selected, you'll be randomly assigned to either the full MORPH program or a measurement-only group. The MORPH program includes one weekly group video session with other participants plus individual coaching calls, along with an activity monitor and app to track your daily steps and set movement goals. You'll also work on eating healthier with a target of losing about 6% of your body weight over 6 months. The study lasts 18 months total, with regular check-ins to measure your pain, activity level, weight, and how you're doing physically.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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