Plain-English translation of NCT06626646 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why people with peripheral artery disease (a condition where arteries in the legs become narrow or blocked) often have worse heart and circulation health outcomes. This study will compare blood samples from 20 people with leg artery disease to 20 people without it, looking for differences in special repair cells that help blood vessels heal and stay healthy.
People with leg artery disease face higher risks of serious complications, yet doctors don't fully understand why some people's bodies struggle more than others. Scientists believe that certain repair cells in the blood become depleted or exhausted in people with this condition, which could explain why they have worse long-term outcomes. This research aims to confirm that theory and eventually help doctors better predict and treat the disease.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll visit the research center once to have a small blood sample drawn — similar to a routine blood test. The researchers will analyze your blood cells and compare them to the other group. There are no follow-up visits or ongoing treatments involved; participation is a single, straightforward visit that typically takes less than an hour.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Canada
Sponsor
Canadian Medical and Surgical Knowledge Translation Research Group
Enrollment target
~40 participants
Started
October 2024
Primary completion
July 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in October 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jack Casey
University of Toronto
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.