Plain-English translation of NCT06627127 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers investigated a new approach to treat obstructive sleep apnea by placing small electrode arrays in the neck and throat. The study tested whether stimulating two functional targets—either nerves or muscles, or a combination of both—could improve breathing during sleep. This was a proof-of-concept study designed to see if this dual-stimulation approach was feasible and whether it reduced sleep apnea events.
Current treatments for obstructive sleep apnea, like CPAP machines, don't work well for everyone, and some patients can't tolerate them. This study explored whether a combination of nerve and muscle stimulation might be more effective than single-target approaches, potentially offering a better option for people who need alternatives.
Participants underwent electrode array placement during a procedure called drug-induced sleep endoscopy, where the research team could observe the airway and measure breathing changes in real time. Participants also completed one or two nights of polysomnography (sleep study) in a lab setting to assess how the stimulation affected breathing and sleep quality with and without the electrodes active. The study measured airflow, sleep stability, and the number of breathing interruptions to determine whether this dual-stimulation approach reduced sleep apnea episodes.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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