Plain-English translation of NCT06627322 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 2 Diabetes research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The REMATCH study is testing whether keeping blood sugar very tightly controlled (at a lower level) can prevent serious heart and kidney problems in people with type 2 diabetes who also have other heart disease risk factors. You would be randomly assigned to either a standard blood sugar control group or an intensive control group; the intensive group also uses a continuous glucose monitor (like the Dexcom G7) to help track blood sugar in real time. Researchers will follow you for up to 4 years to see whether tighter control actually prevents heart attacks, strokes, kidney damage, and other diabetes-related complications.
Many people with type 2 diabetes also have high risk for heart disease and kidney damage, but doctors aren't sure whether pushing blood sugar to very low levels actually prevents these serious complications. This study aims to answer that important question so doctors can give better advice about how hard to push blood sugar control.
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If you join, you'll be randomly assigned to either a standard blood sugar control group or an intensive control group. The standard group will take oral diabetes medications targeting a blood sugar level of 7.0%; the intensive group will take similar medications but also use a continuous glucose monitor (a small sensor worn on your skin) to track blood sugar throughout the day and aim for a tighter target of 6.0%. You'll be followed for up to 4 years with regular visits and blood work, and your health information will be tracked through hospital and national health records to monitor whether you develop any heart or kidney complications.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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