Plain-English translation of NCT06627738 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Carcinoma, Non-Small-Cell Lung research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether adding a treatment called CyberKnife—a specialized machine that delivers very precise, high-dose radiation to specific areas—can improve outcomes for people with advanced non-small cell lung cancer. You would first receive standard chemotherapy combined with regular radiation therapy, and then, if you qualify, receive 5 sessions of the CyberKnife boost over about 2 weeks. Doctors will follow your health for up to 5 years to see how well this combined approach works.
Advanced lung cancer that cannot be surgically removed is difficult to treat with standard therapy alone. Researchers believe that adding this precise, high-dose radiation boost to the usual treatment might destroy remaining cancer cells more effectively and improve survival.
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After you complete your standard chemotherapy and radiation treatment, you would come in for 5 sessions of the CyberKnife boost over about 2 weeks. Then you would have regular follow-up visits for 2 years, with your health and cancer status checked for a total of 5 years after treatment ends. The study is based in France and requires enrollment in the French National Health Insurance system.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
France