Plain-English translation of NCT06633601 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new way to treat advanced breast cancer using an MRI-guided focused ultrasound system combined with standard radiation therapy. Doctors will use ultrasound stimulated microbubbles — tiny gas-filled bubbles that help treatment reach the cancer more effectively — while you lie on an MRI table. You'll then receive standard radiation therapy, which is already a common treatment for this type of cancer.
Advanced breast cancer on the chest wall can be difficult to treat with surgery alone, and doctors want to find ways to make radiation therapy even more effective. This trial explores whether adding the microbubble ultrasound technique can improve how well the treatment works.
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You would come to Sunnybrook Health Sciences Centre for treatment visits. During each visit, you'll lie on an MRI table with an ultrasound device positioned against your breast or chest wall. The doctors will use ultrasound and microbubbles to treat your tumor, followed by standard radiation therapy on the same day. The study plans to enroll about 30 patients total, and your doctor will discuss the exact number of visits and treatment schedule with you based on your individual care plan.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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