Plain-English translation of NCT06638294 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study for people diagnosed with breast cancer that has spread to the leptomeninges—the protective fluid-filled space around the brain and spinal cord. The study collects samples of your blood and spinal fluid, along with information about your tumor's genetics, to help doctors better understand this serious condition and develop more effective treatments. A team of cancer specialists will review your case and provide personalized treatment recommendations based on what they learn from your samples.
Breast cancer spreading to the fluid around the brain is very difficult to treat, and doctors don't yet fully understand the biology of this disease. This study exists to gather biological samples and genetic information that will help researchers learn how this type of cancer behaves and ultimately improve outcomes for future patients.
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You will allow the research team to access your medical records and tumor genetic information. You'll provide a small sample of spinal fluid (less than 2 tablespoons) and blood (about 4 tablespoons) at the start of the study, and possibly again after one month. A team of cancer specialists at Johns Hopkins will review your case and provide treatment recommendations. You'll also answer brief online questionnaires once a month about how you're doing. Your own doctor will decide whether to follow those recommendations, and additional samples may be collected if your treatment changes.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States