Plain-English translation of NCT06641297 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Schizophrenia can affect the white matter in your brain—the tissue that helps different brain regions communicate quickly and efficiently. This trial is testing whether training on a video game called Guitar Hero might help improve how your brain's communication pathways work, especially to help with thinking speed and mental processing.
People with schizophrenia often have slower thinking and processing speeds because of changes in their brain's communication system. Researchers want to see if this treatment can help strengthen those connections and improve these cognitive abilities.
You likely qualify if…
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You would participate in training sessions where you play Guitar Hero, a video game where you match musical notes on a controller. Before and after your training, researchers would use MRI brain scans to see if the white matter in your brain has changed. The study involves 36 people total, and you would be compared with others in the study to see how the training affects brain communication.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
University of Maryland, Baltimore
Enrollment target
~36 participants
Started
January 2025
Primary completion
December 2026
Age range
15 Years – 45 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Joshua J Chiappelli, MD
University of Maryland, Baltimore
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.