Plain-English translation of NCT06641310 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research trial is testing whether regular exercise on a treadmill can help prevent polyps from coming back in people with familial adenomatous polyposis (a genetic condition that causes many polyps in the colon and rectum). You would exercise at home for 26 weeks while researchers monitor your progress and track changes in your polyps through tissue samples and blood tests.
People with familial adenomatous polyposis often develop polyps that can turn into cancer, and current treatments don't work for everyone. This study explores whether exercise might be a simple, safe way to reduce polyp growth and help prevent future cancer.
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You would receive a treadmill to keep in your home and follow a personalized exercise program for 26 weeks, with your activity monitored remotely by exercise specialists. You would visit the clinic twice—once at the start and once 26 weeks later—where you'll have a routine endoscopy exam, provide small rectal tissue samples, and complete blood and stool tests along with questionnaires. The entire study takes about 6 months from start to finish.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
United States